美国佐治亚州神经科学与脑疾病研究博士后职位
Postdoctoral Positions
in neuroscience and brain disorders
Positions are availableto investigate synapse formation, synaptic plasticity and pathologicalmechanisms of brain disorders including schizophrenia and muscular dystrophy. Formore information, please visit our lab’s website:
http://www.georgiahealth.edu/institutes/immag/meilab.Candidates should have PhDs in life sciences and are self-motivated for high-qualityresearch. Strong background in molecular biology, cell biology, biochemistry,electrophysiology, and/or behavioral analysis is ideal but not essential. TheGeorgia Regents University (previously Medical College of Georgia andGeorgia Health Sciences University) is located in Augusta, Georgia, a historicalcity on the Savannah River famous for the Masters golf tournament and enrichedlife. Interested candidates should send CV and a brief statement ofresearch interests to Lin Meiat .
本文来医学生
Selectedarticles:
Y.Z. Huang et al., Regulation of neuregulinsignaling by PSD-95 interacting with ErbB4 at CNS synapses. Neuron 26:443-455, 2000
Z.G. Luo et al., Regulation of AChRClustering by Dishevelled Interacting with MuSK and PAK1. Neuron 35:489-505, 2002.
R.-S. Woo et al., Neuregulin-1 EnhancesDepolarization-Induced GABA Release. Neuron54:599-610, 2007
X.-M. Li et al., Retrograde regulation ofmotoneuron differentiation by muscle β-catenin. Nature Neurosci. 11:262-268, 2008.
S. Luo et al., HSP90β Regulates RapsynTurnover and Subsequent AChR Cluster Formation and Maintenance. Neuron 60:97-110, 2008
B. Zhang et al., LRP4 serves as aco-receptor of agrin. Neuron60:285-297, 2008
L. Wen et al., Neuregulin 1 regulatespyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons. Proc. Nat. Acad. Sci. 107:1211-1216,2010
A. Ting et al., Neuregulin 1 promotesexcitatory synapse development specifically in GABAergic interneurons. J. Neurosci. 31:15-25, 2011.
G.H. Tan et al., Neuregulin1 represseslimbic epileptogenesis via activation of ErbB4 signaling inparvalbumin-positive interneurons. NatureNeurosci. 15:258-266, 2012
Y. Zong et al., Structural basis ofneuron-specific regulation of postsynaptic differentiation. Genes & Development. 26:247-258,2012 (Cover)
H.T. Wu et al., Distinct Roles of Muscleand motoneuron LRP4 in Neuromuscular Junction Formation. Neuron, 75:94-107, 2012.
Y. Tao et al., Erbin interacts with TARPgamma-2 for surface expression of AMPA receptors in cortical interneurons. Nature Neurosci. 16:290-299, 2013.
D.M. Yin et al., Reversal ofschizophrenia-like deficits in neuregulin 1 transgenic mice. Neuron 78:644-657, 2013.
C. Shenet al., Immunization with LRP4 induces myasthenia gravis in mice. J. Clin.Invest. (in press).
Selectedreviews:
L. Mei and W.C. Xiong. Neuregulin-1signaling in neural development, synaptic plasticity and schizophrenia. Nature Rev. Neurosci. 9:437-452, 2008
H. Wu, Wen C. Xiong, L. Mei. To build asynapse: Signaling pathways in neuromuscular junction assembly. Development 137:1017-1033, 2010.
D.M. Yin, W.C. Xiong, L. Mei. Adolescentdopamine slows spine maturation. NatureNeurosci, 16:1514-1516, 2013.
L. Mei, K. Nave. A neuregulin network inthe nervous system. Neuron, 2014.
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